Genome is an apocalypse/science-fiction roleplay that takes place in the year 2400 in Florida. It was created by Osiris and Doom Mantis. The roleplay goes behind the life of Emperor Leonardo Murtaugh IV, who is insane, and the life of his brother, Barc Murtaugh, as well as the lives of various rebels. The roleplay was named "Genome" because of the genetic experiments preformed by Emperor Leonardo Murtaugh IV, Emperor Leonardo Murtaugh III, and even Emperor Barc Murtaugh, eventually. Genome takes place after a nuclear apocalypse in 2030, followed by a lack-of-resources apocalypse and two meteor strikes. Genome's setting is in an alternate universe where dragons and other mythical creatures exist, along with two fictional continents.